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tf  (R&D Systems)


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    Structured Review

    R&D Systems tf
    Tf, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+human+tf/pm41850278-177-211-214?v=R%26D+Systems
    Average 94 stars, based on 2 article reviews
    tf - by Bioz Stars, 2026-07
    94/100 stars

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    Image Search Results


    Delivery of tisotumab or tiso-IR700 and efficacy of in vivo TF-targeted NIR-PIT in the HPAF-II subcutaneous xenograft model. A , Tumors were harvested 24 h after injecting tiso-DIG or isotype-DIG into mice and the distribution in HPAF-II tumors was examined by multiplex immunohistochemistry ( n = 4; images, × 200; scale bar, 100 μm). DIG and pCK are shown in green and purple, respectively. tiso-DIG, digoxigenin (DIG)-conjugated tisotumab. B , In vivo fluorescence imaging of tiso-IR700. Representative fluorescence images at 700 nm in an HPAF-II tumor bearing mouse. All images were acquired at the indicated time points after injecting tiso-IR700 into mice. AU, arbitrary units. C , Quantitative analysis of target-to-background ratio after injecting tiso-IR700 ( n = 5). D , Treatment schedule. E , Representative 700-nm fluorescence images before and after NIR-PIT. F , Tumor volume curves ( n = 10–11; mean ± SEM; repeated measures two-way repeated measures ANOVA followed by Tukey's test); *, p < 0.05; **, p < 0.01; *** p < 0.001; ****, p < 0.0001 versus the Control group. G , Survival curves ( n = 10–11, log-rank test with Bonferroni correction); ***, p < 0.001

    Journal: Cancer Immunology, Immunotherapy : CII

    Article Title: Tissue factor targeted near-infrared photoimmunotherapy: a versatile therapeutic approach for malignancies

    doi: 10.1007/s00262-024-03903-2

    Figure Lengend Snippet: Delivery of tisotumab or tiso-IR700 and efficacy of in vivo TF-targeted NIR-PIT in the HPAF-II subcutaneous xenograft model. A , Tumors were harvested 24 h after injecting tiso-DIG or isotype-DIG into mice and the distribution in HPAF-II tumors was examined by multiplex immunohistochemistry ( n = 4; images, × 200; scale bar, 100 μm). DIG and pCK are shown in green and purple, respectively. tiso-DIG, digoxigenin (DIG)-conjugated tisotumab. B , In vivo fluorescence imaging of tiso-IR700. Representative fluorescence images at 700 nm in an HPAF-II tumor bearing mouse. All images were acquired at the indicated time points after injecting tiso-IR700 into mice. AU, arbitrary units. C , Quantitative analysis of target-to-background ratio after injecting tiso-IR700 ( n = 5). D , Treatment schedule. E , Representative 700-nm fluorescence images before and after NIR-PIT. F , Tumor volume curves ( n = 10–11; mean ± SEM; repeated measures two-way repeated measures ANOVA followed by Tukey's test); *, p < 0.05; **, p < 0.01; *** p < 0.001; ****, p < 0.0001 versus the Control group. G , Survival curves ( n = 10–11, log-rank test with Bonferroni correction); ***, p < 0.001

    Article Snippet: Tisotumab, an anti-human TF recombinant monoclonal antibody (mAb), was purchased from Creative Biolabs Inc. (Shirley, NY, USA).

    Techniques: In Vivo, Multiplex Assay, Immunohistochemistry, Fluorescence, Imaging, Control